Sorry to revive this thread but I have to voice my opinion
When I think perfect armament I somehow always end up at the longnosed 190s:
D-9: Perfect multi-role armament with a bias towards anti-fighter work. 2 20mm and 2 13mm placed reasonably close together and close to the ReVi-sight. Not as unforgiving as the 109s all-centered armament, though. No wing mounted cannons that jam, no flexing, no adverse effect on roll-rates.
Another option that'd be interesting is to replace the 13mm MGs with a third MG151 firing through the spinner: That would reduce drag a bit (no bumps on the cowling) and make aiming more predictable as all guns would have roughly the same trajectory. Also you can't argue with a good engine cannon (assuming you can make one that is reliable), at least in theory it seems like the best place for a gun overall. I think they tried that armament on one of the Doras too.
D-13(???): Good allround armament, this time biased towards intercepting bombers: The centerline 30mm inflicts serious damage and the two 20mm do their part and provide more than self-defense against fighters.